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Effect of rTGF-β1 administration on the survival of mice infected with 1 LD50 of S. typhimurium (8 × 105 CFU/mouse). Ten mice were injected i.p. with PBS 2 h before infection with S. typhimurium (×), and 10 mice were injected i.p. with 0.5 μg of rTGF-β1 2 h before infection with S. typhimurium (○). ∗, P < 0.01 with respect to infected, nontreated mice.
