Fig. 3. Effect of dietary salt restriction on blood pressure rise.
Systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) before and after treatment with the VEGF inhibitor without and with dietary sodium restriction (DSR). Visits: 1: baseline; 2: end of treatment cycle 1; 3: baseline treatment cycle with dietary sodium restriction; 4: end treatment cycle with DSE. In purple, mean BP values. Patients 14 and 16 received amlodipine during the first treatment cycle because of a rise in SBP > 170 mmHg, which could be discontinued during DSR. Patients 1, 4, 11 and 15 received amlodipine or doxazosin during the first treatment cycle and continued during second treatment cycle.