TABLE 2.
Pathways enriched by gene set enriched pathways of differentially expressed proteins in PSP compared to HC. Differentially expressed proteins selected by both volcano plot and bootstrap ROC analysis were used for this analysis
| Term | Count | a PH | % | p Value |
|---|---|---|---|---|
| Parkinson's disease | 25 | 142 | 17.6 | 3.40E‐18 |
| Oxidative phosphorylation | 24 | 133 | 18.0 | 1.10E‐17 |
| Alzheimer's disease | 25 | 168 | 14.9 | 1.90E‐16 |
| Huntington's disease | 26 | 192 | 13.5 | 3.90E‐16 |
| Non‐alcoholic fatty liver disease (NAFLD) | 23 | 151 | 15.2 | 2.80E‐15 |
| Ribosome | 19 | 136 | 14.0 | 6.40E‐12 |
| Metabolic pathways | 42 | 1219 | 3.4 | 2.80E‐06 |
| Cardiac muscle contraction | 9 | 75 | 12.0 | 3.20E‐05 |
| Glutamatergic synapse | 7 | 114 | 6.1 | 1.20E‐02 |
| Citrate cycle (TCA cycle) | 4 | 30 | 13.3 | 1.30E‐02 |
a
PH, the total number of proteins in the pathway.