A. Family RDHM-05, CW07, 5543, 5377 and 6772. Parental consanguinity, double bar; square, male; circle, female; diamond, sex unknown; filled, affected; unfilled, unaffected; backslash, deceased.
B. Photographs of patients from family CW07 showing dry, acneiform lesions of the skin, RDHM-05, 5543, 5377 and 6772 showing thin upper lips.