TABLE 1.
OprF-I-specific IgG antibody titer determined by ELISA
| Time point and statistic | Titer for dose of:
|
|||
|---|---|---|---|---|
| 20 μg | 50 μg | 100 μg | 500 μg | |
| Day 0 | ||||
| Mean | 294 | 195 | 318 | 391 |
| Median | 295 | 194 | 240 | 280 |
| SD | 125 | 94 | 297 | 291 |
| Minimum/maximum | 100/494 | 100/321 | 100/1,020 | 172/1,030 |
| Day 14 | ||||
| Mean | 5,580 | 18,375 | 18,516 | 40,258 |
| Median | 1,995 | 2,530 | 16,350 | 16,510 |
| SD | 10,721 | 46,335 | 15,844 | 53,359 |
| Minimum/maximum | 581/32,000 | 492/133,000 | 1,620/43,600 | 1,290/130,000 |
| Day 42 | ||||
| Mean | 11,778 | 24,965 | 21,262 | 52,539 |
| Median | 6,650 | 5,870 | 21,250 | 31,800 |
| SD | 12,948 | 47,332 | 10,546 | 47,404 |
| Minimum/maximum | 1,630/40,200 | 773/140,000 | 3,000/38,100 | 8,310/139,000 |
| Day 70 | ||||
| Mean | 27,262 | 44,318 | 42,412 | 80,456 |
| Median | 13,800 | 15,125 | 43,975 | 49,450 |
| SD | 28,998 | 58,733 | 16,680 | 84,806 |
| Minimum/maximum | 5,790/88,650 | 1,130/107,000 | 21,100/70,150 | 11,595/228,000 |
| After 6 mo | ||||
| Mean | 10,146 | 19,922 | 13,573 | 22,774 |
| Median | 4,890 | 3,040 | 12,400 | 10,365 |
| SD | 10,599 | 39,007 | 7,963 | 31,256 |
| Minimum/maximum | 985/31,300 | 351/107,000 | 2,050/26,300 | 1,920/95,900 |
| Booster day 14 | ||||
| Mean | 22,290 | 34,910 | 78,014 | 129,388 |
| Median | 15,500 | 19,800 | 51,200 | 112,100 |
| SD | 19,686 | 40,370 | 69,138 | 91,281 |
| Minimum/maximum | 3,500/61,200 | 471/119,000 | 21,600/220,000 | 24,900/286,000 |