FIG. 4.

Haematoxylin-eosin staining of tissue sections corresponding to samples obtained from loops infected for 8 h with BS176 (panel 1) and M90T (panels 2, 3, and 4). Panel 2 corresponds to a sample from a rabbit treated with the control MAb, whereas panels 3 and 4 correspond to samples from rabbits treated with anti-IL-8 MAb WS-4. In panel 2, arrowheads define areas in which PMNs are streaming through the lamina propria and the epithelium. In panel 3, the arrowhead points to mononuclear cells infiltrating the epithelium in animals in which IL-8 has been neutralized. Bars, 10 μm.