Table 3.
Sub-group analysis of altered parameters in HIV-infected cases with relation to serum vitamin B12 concentration
| Parameters | Deficient Vitamin B12 levels (<200 pg/ml) (n=24) | Sub-normal VitaminB12 levels (200-300 pg/ml) (n=16) | Normal Vitamin B12 levels (>300 pg/ml) (n=15) | P a |
|---|---|---|---|---|
| Hb (gm/dl) | 9.65±2.62 | 10.97±2.64 | 13.59±2.18 | 0.008 |
| RBC (million cells/cu. mm) | 3.78±0.96 | 4.28±1.13 | 4.6±0.78 | 0.239 |
| PCV% | 33.41±9.83 | 37.83±9.96 | 45.02±6.19 | 0.041 |
| MCV (fl) | 99.58±15.08 | 90.72±9.01 | 88.15±8.81 | 0.037 |
| MCH (pg) | 25.63±2.54 | 25.9±2.94 | 29.91±4.00 | 0.007 |
| MCHC (gm/dl) | 29.16±2.38 | 29.22±2.06 | 30.16±1.98 | 0.530 |
| RDW CV(%) | 16.74±1.89 | 16.08±2.16 | 14.62±1.26 | 0.042 |
| Absolute lymphocytes/cu.mm | 1070±600.47 | 1866.6±890.15 | 2178.75±647.03 | 0.010 |
| CD4 count (cells/μL) | 121.2±15.06 | 273.2±141.83 | 483.2±140.69 | <0.001 |
| CD8 count (cells/μL) | 392.34±25.36 | 1147.6±804.75 | 1056.48±375.39 | 0.012 |
| Ferritin (ng/ml) | 1191.14±175.38 | 437.9±55.87 | 150.88±16.42 | 0.006 |
| CRP (mg/L) | 27.26±3.11 | 8.23±1.27 | 3.99±0.18 | 0.005 |
aP<0.05 is significant