Table 1. Characteristics of eligible studies included in this meta-analysis.
| Author (Year) | Location | Study design |
Participants
number |
Age
(years) |
Dental status | Outcomes | Cancer type | Assessment method |
Follow-up
(year) |
Adjusted variables |
|---|---|---|---|---|---|---|---|---|---|---|
| Hujoel et al. 2003 | USA | Prospective study | 11,328 | 25–74 | Dental examination | Cancer mortality | breast, prostate, lung & bronchus, colon & rectum, total cancer | ICD-9 | 18 | age, gender, education, socioeconomic level, race, smoking, alcohol consumption, vitamin consumption, et al. |
| Michaud et al. 2008 | USA | Prospective study | 48,375 | 40–75 | Self-reported | Cancer incidence | prostate, lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 17.7 | age, race, smoking, alcohol consumption, vitamin consumption, body mass index, diabetes, physical activity, et al. |
| Arora et al. 2010 | Swedish | Prospective study | 15,333 | 38–77 | Self-reported | Cancer incidence | breast, prostate, colon & rectum, total cancer | ICD | 27 | age, gender, education, smoking, alcohol consumption, body mass index, diabetes, et al. |
| Ahn et al. 2012 | USA | Prospective study | 12,605 | ≥17 | Dental examination | Cancer mortality |
colon & rectum | ICD-10 | 12 | age, gender, education, race, smoking, body mass index, et al. |
| Mai et al. 2014 | USA | Prospective study | 77,485 | 50–79 | Self-reported | Cancer mortality |
lung & bronchus | ICD-O-2 | 6.8 | age, education, race, smoking, alcohol consumption, body mass index, physical activity, et al. |
| Wen et al. 2014 | China | Prospective study | 1 million | >20 | Dental examination | Cancer incidence | breast, lung & bronchus, total cancer | ICD-9 | 14 | age, gender, et al. |
| Chrysanthakopoulos et al. 2016 | Greek | Retrospective study | 200 | ≥48 | Dental examination | Cancer incidence | lung & bronchus | Medical records or histological examination | 2 | age, gender, education, socioeconomic level, smoking, et al. |
| Chung et al. 2016 | China | Prospective study | 40,140 | ≥40 | Dental examination | Cancer incidence | breast, total cancer | ICD-9 | 5 | socioeconomic level, diabetes, et al. |
| Freudenheim et al. 2016 | USA | Prospective study | 73,737 | 50–79 | Self-reported | Cancer incidence | breast | Medical records or histological examination | 6.7 | age, education, race, smoking, alcohol consumption, body mass index, physical activity, et al. |
| Mai et al. 2016 | China | Prospective study | 1,337 | 53–85 | Dental examination | Cancer incidence | breast, lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 12.2 | age, smoking, et al. |
| Michaud et al. 2016 | USA | Prospective study | 19,933 | 40–75 | Self-reported | Cancer incidence | prostate, lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 26 | age, race, smoking, alcohol consumption, body mass index, diabetes, physical activity, et al. |
| Dizdar et al. 2017 | Turkey | Prospective study | 280 | ≥35 | Dental examination | Cancer incidence | breast, prostate, lung & bronchus, total cancer | Medical records or histological examination | 12 | age, gender, et al. |
| Han et al. 2017 | Korea | Retrospective study | 22,948 | ≥19 | Dental examination | Cancer incidence | breast, lung & bronchus, colon & rectum, total cancer | self-reported | 2 | education, socioeconomic level, smoking, alcohol consumption, et al. |
| Lee et al. 2017 | Korea | Prospective study | 934 | ≥40 | Dental examination | Cancer incidence | prostate, colon & rectum | ICD-10 | 12 | age, gender, socioeconomic level, smoking, alcohol consumption, diabetes, physical activity, et al. |
| Momen-Heravi et al. 2017 | USA | Prospective study | 121,700 | 30–55 | Self-reported | Cancer incidence | colon & rectum | ICD-9 | 19 | age, race, smoking, alcohol consumption, vitamin consumption, body mass index, diabetes, et al. |
| Nwizu1 et al. 2017 | USA | Prospective study | 65,869 | 54–86 | Self-reported | Cancer incidence | breast, lung & bronchus, colon & rectum, total cancer | ICD or Medical records | 8.32 | age, smoking, body mass index, et al. |
| Sfreddo et al. 2017 | Brazil | Retrospective study | 201 | ≥18 | Dental examination | Cancer incidence | breast | ICD-10 or Medical records | 2.2 | age, smoking, body mass index, et al. |
| Chou et al. 2018 | China | Retrospective study | 67,672 | ≥18 | Dental examination | Cancer incidence | colon & rectum | ICD-9 | 10 | age, gender, education, socioeconomic level, diabetes, et al. |
| Heikkilä et al. 2018 | Finland | Prospective study | 68,273 | ≥29 | Dental examination | Cancer mortality |
breast, prostate, lung & bronchus, total cancer | ICD-10 | 10.1 | age, gender, socioeconomic level, diabetes, et al. |
| Hu et al. 2018 | China | Prospective study | 212,974 | ≥18 | Dental examination | Cancer incidence | colon & rectum | ICD-9 | 3 | age, gender, et al. |
| Lee et al. 2018 | Korea | Retrospective study | 42,871 | 30–45 | Self-reported | Cancer incidence | colon & rectum | Medical records or histological examination | 3 | age,sex,BMI, DM, HbA1c, HTN, LDL ,waist,alcohol intake,smoking status and pack-years. |
| Michaud et al. 2018 | USA | Prospective study | 7,466 | 44–66 | Dental examination | Cancer incidence | breast, prostate, lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 14.7 | age, field center, education level, smoking status, smoking duration, drinking status, body mass index, and diabetes status |
| Güven et al. 2019 | Turkey | Prospective study | 5,199 | ≥50 | Dental examination | Cancer incidence | lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 7.2 | age, gender, et al. |
| Lu et al. 2019 | USA | Prospective study | 15,792 | 44–66 | Dental examination | Cancer incidence and mortality | Lung & bronchus, colon & rectum, total cancer | Medical records or histological examination | 4 | age, education, race, smoking, alcohol consumption, diabetes, et al. |
| Tai et al. 2019 | China | Prospective study | 714,246 | No metion | Dental examination | Cancer incidence | lung & bronchus | ICD-9 | ≥10 | no |
| Yoon et al. 2019 | USA | Retrospective study | 84,797 | 40–79 | Self-reported | Cancer incidence | lung & bronchus | ICD-10 | 8 | education, socioeconomic level, smoking, alcohol consumption, body mass index, et al. |
| Huang et al. 2020 | USA | Prospective study | 6,034 | ≥40 | Dental examination | Cancer mortality | total cancer | Medical records or histological examination | 21.3 | age, gender, education, socioeconomic level, race, smoking, body mass index, diabetes, et al. |
Notes.
ICD: International Classification of Diseases.