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. 2022 Oct 27;16:996368. doi: 10.3389/fnins.2022.996368

TABLE 2.

Enrichment analysis of differentially expressed IRGs in kainite-induced epilepsy.

Ontology ID Description GeneRatio BgRatio P-value p.adjust q-value
BP GO:0050900 Leukocyte migration 15/34 340/23,210 3.25e−19 6.61e−16 2.83e−16
BP GO:0032103 Positive regulation of response to external stimulus 14/34 312/23,210 5.14e−18 5.22e−15 2.23e−15
BP GO:0030595 Leukocyte chemotaxis 12/34 211/23,210 1.07e−16 7.24e−14 3.10e−14
BP GO:0097529 Myeloid leukocyte migration 11/34 207/23,210 5.20e−15 2.64e−12 1.13e−12
BP GO:0060326 Cell Chemotaxis 12/34 299/23,210 7.14e−15 2.90e−12 1.24e−12
CC GO:0045121 Membrane raft 7/34 364/2,3436 7.72e−07 2.34e−05 1.47e−05
CC GO:0098857 Membrane microdomain 7/34 365/2,3436 7.86e−07 2.34e−05 1.47e−05
CC GO:0098589 Membrane region 7/34 377/23,436 9.76e−07 2.34e−05 1.47e−05
CC GO:0043235 Receptor complex 5/34 394/23,436 2.44e−04 0.003 0.002
CC GO:0070062 Extracellular exosome 3/34 90/23,436 3.01e−04 0.003 0.002
MF GO:0005125 Cytokine activity 12/34 215/22,710 1.74e−16 2.03e−14 1.02e−14
MF GO:0048018 Receptor ligand activity 14/34 489/22,710 3.60e−15 2.10e−13 1.06e−13
MF GO:0008009 Chemokine activity 6/34 44/22,710 4.79e−11 1.87e−09 9.41e−10
MF GO:0001664 G protein-coupled receptor binding 9/34 293/22,710 3.46e−10 1.01e−08 5.10e−09
MF GO:0042379 Chemokine receptor binding 6/34 67/22,710 6.61e−10 1.55e−08 7.79e−09
KEGG mmu04668 TNF signaling pathway 10/33 113/8,910 5.21e−12 7.19e−10 4.22e−10
KEGG mmu04657 IL-17 signaling pathway 9/33 91/8,910 2.55e−11 1.76e−09 1.03e−09
KEGG mmu04620 Toll-like receptor signaling pathway 9/33 100/8,910 6.05e−11 2.29e−09 1.34e−09
KEGG mmu04933 AGE-RAGE signaling pathway in diabetic complications 9/33 101/8,910 6.63e−11 2.29e−09 1.34e−09
KEGG mmu05323 Rheumatoid arthritis 8/33 87/8,910 6.78e−10 1.87e−08 1.10e−08