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. 2022 Nov 7;27(1):249–258. doi: 10.1080/13510002.2022.2139947

Table 3.

Treatment of CKD rat model with ZnO-NP and SPL results in down-regulation of oxidative stress and enhanced antioxidants.

Groups Control CKD SPL ZnO-NPs SPL + ZnO-NPs
GSH (mmol/g) 9.4 ± 2.5 2.5 ± 0.73a 4.44 ± 1.41a 5.78 ± 1.14ab 8.39 ± 1.72bc
SOD (U/g) 324.7 ± 41.21 121.6 ± 37.2a 217.03 ± 34.7ab 260.14 ± 33.8ab 297.6 ± 21.27bc
CAT (U/g) 8 ± 3.32 1.68 ± 0.51a 5.25 ± 1.32ab 6.03 ± 1.21ab 7.36 ± 2.11b
MDA (nmol/g) 11.58 ± 3.33 49.77 ± 11.05a 32.37 ± 5.96ab 24 ± 5.65ab 15.9 ± 4.12bc

Notes: Significant difference compared to corresponding acontrol group, bCKD group, cSPL group, dZnO-NPs group at p < 0.05 by ANOVA and Tukey test.