TABLE 1.

Parameter estimates from the linear regression model for survival days since treatment to death

Model term	Estimate (SE)	P
Intercept	70.35 (8.83)	<0.001
Effect of Keto vs. Control	13.83 (7.01)	0.052
Effect of gemcitabine vs. No gemcitabine	25.76 (7.95)	0.002
Effect of age at the start of treatment (in days, centered at 90)	−0.25 (0.30)	0.406
Effect of male vs. female	−13.19 (7.07)	0.066

Note: Linear regression for survival days since treatment to death was adjusted by sex and age at the start of treatment. There is no censoring in data. Age at the start of treatment is centered at 90 days; thus, the intercept can be interpreted as the predicted survival days since treatment for a female animal taking conventional diet and no gemcitabine, with treatment starting at 90-day old. The estimate for age at the start of treatment can be interpreted as the average increase in outcomes for 1-day increase in age at the start of treatment. Interaction between diet and gemcitabine was excluded from models due to nonsignificance. The two-way and three-way interactions between sex and treatments (diet, gemcitabine) are nonsignificant.