Table 2.

Percent of 148 regions showing statistical significance.

Effects	Harmonization methods				Chi-squared test
	LMEINT	LMEINT+SLP	ComBat	ComBat-GAM	statistics	p (Bonferroni corr.)
Age	98.0	76.4	99.3	99.3	89.658	<0.001
Diagnosis	1.4	1.4	3.4	20.9	63.704	<0.001
Age × Diagnosis	0	0	0	2.7	12.082	0.007
Sex	17.6	19.6	29.1	29.1	9.114	0.028
Sex × Diagnosis	0	0	0	0	NA	NA

Note: LME_INT, LME models site-specific random intercept. LME_INT+SLP, LME models both site-specific random intercepts and age-related random slopes.