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. 2022 Nov 10;17(11):e0276396. doi: 10.1371/journal.pone.0276396

Table 4. Summary of individual study impact estimates.

Title Author Publication Year Impact on mean HbA1c Diabetes-related hospitalisation rate Impact on treatment adherance Impact on mean weight/BMI
Community health workers improve diabetes care in remote Australian indigenous communities: Results of a pragmatic cluster randomized controlled trial McDermott et al. 2015 −1.0% (intervention group: 10.8% to 9.8%) vs −0.2% (control group 10.6% to 10.3%) (p-value  = 0.018) Not Assessed Adherence to all meds Intervention: 53% (95% CI 37.6–56.2) to 57% (43.7–62.8); Control 55% (45.1–64.9) to 41% (38.0–59.6) Intervention: 89.7kg to 91.0kg; Control 91.4kg to 87.4kg control (72) -1.5kg (-2.7kg to -2.3kg 95% CI); intervention (71) -0.6kg (-2.0kg to 0.8kg)
Pragmatic randomised trial of a 12-week exercise and nutrition program for Aboriginal and Torres Strait Islander women: Clinical results immediate post and 3 months follow-up Canuto et al. 2012 3 months follow up: Waitlist group: mean 6.6% (95% CI 5.9–7.2%) -> 6.4% (5.5–7.3%) Intervention group mean 6.2% (5.7–6.6%) -> 6.0% (5.4–6.6%) Not Assessed At 3 months follow-up Intervention group anthropometric follow up attendance: 53% vs 59% for control; Pathology follow-up intervention group 49% vs 47% for control 3 months follow up:WL group 94.8kg (95% CI 86.3–103.4) -> 79.2kg (73.3–85.0) Intervention group 92.6kg (84.5–100.6) -> 95.9kg (86.5–105.2) (influenced by loss to follow up)
Analysis of a primary care led diabetes annual review programme in a multi ethnic cohort in Wellington, New Zealand Smith et al. 2011 Increased 0.03% (8.0% to 8.0%); linear term for curvilinear relationship was -0.05 (-0.10 to -0.015 95% CI) Not Assessed Oral hypoglycaemic use: (219/298) 73.5% -> (259/298) 86.9% (p < 0.001); Insulin use (31/298) 10.4% -> (56/298) 18.8% (p < 0.001); No insulin in participants with HbA1c >/ = 8% (106/129) 82.2% -> 87/126 (69.1%) Mean change (Maori) -1.4kg 94.8 (SD 19.9) to 93.4 (SD 21.4) Linear term (95% CI -0.31 to -0.17) -0.24kg
A patient-centred clinical approach to diabetes care assists long-term reduction in HbA1c Titchener 2014 (mmol/mol) Baseline = 100, Post-discharge: Not Assessed Not Assessed Not Assessed
3 months = 77 (p-value <0.001)
6 months = 77
9 months = 75
12–15 months = 87
18–24 months = 73
(no p-value for outcomes after 3-months follow-up)
Recruitment and effectiveness by cohort in a case management intervention among American Indians and Alaska Natives with diabetes Pratte et al. 2019 -0.14% (2006), Not assessed Increased healthy diet (p = 0.32) (0.05, 0.11, 0.10 increase in score 2006, 07, 08), decreased unhealthy diet (p = 0.75) (-0.15, -0.17, -0.13), increased physical activity (p = 0/0007) (0.43, 0.09, 0.07), decreased smoking (p = 0.37) (-3.9%, -2.9%, -3.1%) BMI -0.21 (2006), -0.18 (2007), -0.16 (2008) p-value 0.93
-0.18% (2007),
-0.31% (2008) (p-value = 0.17)
A home-based educational intervention improves patient activation measures and diabetes health indicators among Zuni Indians Shah et al. 2015 8.12 +- 2.16 —> 6 months follow-up 7.39 +- 1.6 (p-value = 0.001) Not Assessed Not Assessed BMI 33.8 +- 8.4 —> 32.4 +- 8.2 (p = 0.001)
Talking Circles to Improve Diabetes Self-care Management Wilken et al. 2017 No baseline data; (95% CI and P = 0.126) Intervention: Not Assessed At 3 months:Intervention group follow-up attendance 70% vs Control group 26.3% (p-value = 0.01) Mean weight (lb) (95% CI) (p value 0.133) Intervention 3 months 211.5 (208.4–214.6), 6 months 210.1 (208.2–212.1), 9 months 208.0 (204.0–212.1), 12 months 206.7 (202.1–211.3); control 3 months 206.7 (203.9–209.4), 6 months 203.5 (198.7–208.4), 9 months 201.6 (196.4–206.8), 12 months 208.2 (197.7–218.6)
3 months 8.69 (8.21–9.17),
6 months 9.02 (8.44–9.60),
9 months 8.85 (8.30–9.40),
12 months 8.72 (7.96–9.47)
Control:
3 months 9.00 (8.27–9.72),
6 months 9.83 (9.08–10.6),
9 months 9.62 (8.71–10.5),
12 months 9.62 (8.85–10.4)