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. 2022 Oct 10;14(20):8205–8220. doi: 10.18632/aging.204329

Table 2. Characterization of Sirt1 peak signal and interval distribution in PFC from shorter- (18-20yo) and longer-lived (>23 yo) elder rhesus macaques.

Description Act regions Shorter- Sirt1 Rh Shorter- Sirt1 Rh (%) Longer- Sirt1 Rh Longer- Sirt1 Rh (%) Input overlap Input overlap (%)
Total # Intervals in Build 307 110 34
# Intervals within -10000/+10000 bp of Genes 274 226 73.62% 75 68.18% 12 35.29%
# Intervals NOT within -10000/+10000 bp of Genes 137 81 26.38% 35 31.82% 22 64.71%
# NCBI Genes with Intervals within -10000/+10000 bp 411 347 107 10
# Intervals within Promoter Region
(-7500/+2500 bp of NCBI Gene Start)
208 181 58.96% 52 47.27% 6 17.65%
# Intervals 500 bp of NCBI Tx Start 145 129 42.02% 37 33.64% 1 2.94%
# NCBI Genes with intervals in Promoters
(-7500/2500 bp of start)
304 267 69 10