Table 3. Statistical comparisons of the following variables: increased WBC/mm3, increased protein concentration, percentage detection of the SARS-CoV-2 genome, percentage of type 2 and type 4 OCBs and percentage of cases with increased CSF IL-6, among patients classified as having encephalitis, encephalopathy or inflammatory syndromes, using the chi-square test or Fisher's exact test.
Increased CSF WBC/mm3 | Increased CSF protein concentration | RT-PCR | OCB type 2 | OCB type 4 | IL-6 | |
---|---|---|---|---|---|---|
Encephalitis | 39 of 74 (52.7%) | 24 of 54 (42.29%) | 6 of 35 (17.14%) | 0 of 2 (0%) | 0 of 2 (0%) | 33 of 39 (84.61%) |
Encephalopathy | 24 of 172 (12.24%) | 42 of 153 (29.41%) | 5 of 144 (3.35%) | 2 of 42 (4.65%) | 23 of 43 (53.48%) | 3 of 3 (100%) |
Inflammatory syndrome | 18 of 48 (37.5%) | 29 of 48 (41.66%) | 1 of 31 (3.22%) | 0 of 9 (0%) | 2 of 9 (22.22%) | 2 of 2 (100%) |
P | < 0.05 | < 0.05 | < 0.05 | NS | NS | NS |
WBC: white blood cells; SARS-CoV-2: severe acute respiratory coronavirus 2; CSF: cerebrospinal fluid; IL-6: interleukin 6; OCB: oligoclonal bands; RT-PCR: detection of the genome of SARS-CoV-2 in the CSF with reverse transcriptase polymerase chain reaction; Il: interleukin; NS: not significant.