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. 2022 Feb 28;80(3):296–305. doi: 10.1590/0004-282X-ANP-2021-0117

Table 3. Statistical comparisons of the following variables: increased WBC/mm3, increased protein concentration, percentage detection of the SARS-CoV-2 genome, percentage of type 2 and type 4 OCBs and percentage of cases with increased CSF IL-6, among patients classified as having encephalitis, encephalopathy or inflammatory syndromes, using the chi-square test or Fisher's exact test.

Increased CSF WBC/mm3 Increased CSF protein concentration RT-PCR OCB type 2 OCB type 4 IL-6
Encephalitis 39 of 74 (52.7%) 24 of 54 (42.29%) 6 of 35 (17.14%) 0 of 2 (0%) 0 of 2 (0%) 33 of 39 (84.61%)
Encephalopathy 24 of 172 (12.24%) 42 of 153 (29.41%) 5 of 144 (3.35%) 2 of 42 (4.65%) 23 of 43 (53.48%) 3 of 3 (100%)
Inflammatory syndrome 18 of 48 (37.5%) 29 of 48 (41.66%) 1 of 31 (3.22%) 0 of 9 (0%) 2 of 9 (22.22%) 2 of 2 (100%)
P < 0.05 < 0.05 < 0.05 NS NS NS

WBC: white blood cells; SARS-CoV-2: severe acute respiratory coronavirus 2; CSF: cerebrospinal fluid; IL-6: interleukin 6; OCB: oligoclonal bands; RT-PCR: detection of the genome of SARS-CoV-2 in the CSF with reverse transcriptase polymerase chain reaction; Il: interleukin; NS: not significant.