Evidence for possible genetic rearrangements revealed by sequence alignments of the B. burgdorferi 297 OspE and OspF homologs and Elp proteins. ClustalW alignments of OspE and p21 (A); OspF, BbK2.10, and BbK2.11 (B); and ElpA1, ElpA2, ElpB1, and ElpB2 (C). In panel A, arrows and boldface type indicate tandem duplication and possible insertion-deletion, respectively. In panel C, boldface sequences indicate potential insertions-deletions described in text, while tandem repeats in ElpB2 are underlined. In all of the panels, identical and similar residues are shaded.