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. 2022 Nov 3;2022:6207701. doi: 10.1155/2022/6207701

Figure 3.

Figure 3

C8 altered the proliferation and migration of CC cell lines and malignant behavior related molecules at the mRNA levels. (a, c). C8 (concentration of 30 μM) inhibited the proliferation of HeLa and GH354 cells. (b, d). C18 (concentration of 30 μM) had no effect on the proliferation of HeLa and GH354 cells. (e–h). C8 inhibited cervical cancer cell migration and healing rate compared to the control group. Images are representative of 3 biological replicates. All values represent the mean ± standard deviation (SD). Scale bar in (e, g) is equal to 50 μm(micrometer). (i, j). RT-qPCR analysis of the mRNA expression levels of E-cadherin, N-cadherin, Vimentin, and MMP9 under C8 intervention in HeLa and GH354 cells. Images are representative of 3 biological replicates. All values represent the mean ± standard deviation (SD). ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001.