Table 1.

Top 30 drug-gene interactions in the severe asthma (according to FDR value).

Category	ID	Name	Source	P value	q-value FDR B&H	Hit in query list
Drug	CID000000283	Formate	Stitch	0.000006067	0.01473	MRPL1, CPSF4, PLK1, CAT
Drug	CID000102191	V0509	Stitch	0.000006156	0.01473	ADCY4, CYFIP1, IFT57, CAT
Drug	CID000001152	Tungstate	Stitch	0.00001666	0.02193	ADCY4, CPSF4, CAT
Drug	CID005281571	Purpurogallin	Stitch	0.00002875	0.02193	PLK1, CAT
Drug	CID000001184	AC1L1AWW	Stitch	0.00003613	0.02193	KRT18, CAT
Drug	CID000007120	O-108	Stitch	0.00004013	0.02193	KRT18, CAT
Drug	CID000073665	Prochloraz	Stitch	0.00004906	0.02193	ADCY4, PLK1, CAT
Drug	CID000007243	O-phenylenediamine	Stitch	0.000074	0.02193	CPSF4, CAT
Drug	6912_DN	PF-00562151-00 [351320-12-2]; down 200; 10 μM; MCF7; HT_HG-U133A	Broad Institute CMAP Down	0.00008986	0.02193	PLK1, RNF126, CAT
Drug	CID000014195	Benzyl viologen	Stitch	0.0001111	0.02193	CPSF4, CAT
Drug	CID000075038	AC1L2NWK	Stitch	0.0001181	0.02193	KRT18, CAT
Drug	CID000221491	Light yellow	Stitch	0.0001181	0.02193	KRT18, CAT
Drug	CID000160954	Nitrogen oxides	Stitch	0.0001252	0.02193	CPSF4, CAT
Drug	CID000073040	Lupenol	Stitch	0.00014	0.02193	PLK1, CAT
Drug	CID000000321	Coproporphyrinogen III	Stitch	0.0001478	0.02193	CPSF4, CAT
Drug	CID000169577	Extracted from bacteria	Stitch	0.0001557	0.02193	RAB6A, CAT
Drug	CID000010281	Thymoquinone	Stitch	0.0001639	0.02193	PLK1, CAT
Drug	CTD: D002857	Chromium	CTD	0.0001749	0.02193	PLK1, SMAD4, CAT
Drug	CID000000700	Monoethanolamine	Stitch	0.0002077	0.02193	IFT57, CAT
Drug	CID000439504	AC1L97HB	Stitch	0.0002077	0.02193	CPSF4, CAT
Drug	CID000004441	Naringin	Stitch	0.0002171	0.02193	CPSF4, CAT
Drug	CID000005897	2-Acetylaminofluorene	Stitch	0.0002322	0.02193	CPSF4, IFT57, CAT
Drug	CID000077918	1-Benzylimidazole	Stitch	0.0002365	0.02193	CPSF4, CAT
Drug	CID000012446	Dicarbethoxydihydrocollidine	Stitch	0.0002567	0.02193	KRT18, CAT
Drug	CID000001031	Propanol	Stitch	0.0002885	0.02193	ADCY4, CAT
Drug	CID000002612	AC1L1E2H	Stitch	0.0003108	0.02193	ADCY4, CAT
Drug	CID000000866	Dl-lysine	Stitch	0.0003129	0.02193	ADCY4, MRPL1, CAT
Drug	CID000031250	Dltp	Stitch	0.0003222	0.02193	PLK1, CAT
Drug	CID000062638	Tellurium dioxide	Stitch	0.0003338	0.02193	CPSF4, CAT
Drug	CID000007967	Cyclohexanone	Stitch	0.0003338	0.02193	CPSF4, CAT