Table 2.
CS1 study. Multivariable models (logistic and Cox regressions) with variables associated with the “non-responder” group (b-CPAP failure in the general ward)
| Logistic regression 1* | Cox regression 1* | Logistic regression 2** | Cox regression 2** | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| VIF | Odds ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | VIF | Odds ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| Age (months) | 1.1 | Excluded by forward selection | - | Excluded by forward selection | - | 1.1 | 1.14 (0.46–2.83) | 0.78 | 0.96 (0.51–1.80) | 0.89 |
| BROSJOD scale (points) | - | - | - | - | - | 1.1 | 1.20 (0.67–2.16) | 0.53 | 1.08 (0.74–1.59) | 0.68 |
| HR pre-CPAP (bpm) | 2.3 | Excluded by forward selection | - | Excluded by forward selection | - | - | - | - | - | - |
| RR pre-CPAP (bpm) | 2.2 | Excluded by forward selection | - | Excluded by forward selection | - | - | - | - | - | - |
| BROSJOD Scale at 60 min | - | - | - | - | - | 1.1 | 2.71 (1.31–5.62) | < 0.01 | 2.23 (1.59–3.12) | < 0.01 |
| HR at 60 min (bpm) | 1.9 | 1.10 (1.01–1.20) | 0.02 | 1.06 (1.02–1.09) | < 0.01 | - | - | - | - | - |
| RR at 60 min (rpm) | 2.2 | 1.10 (0.99–1.22) | 0.06 | 1.07 (1.01–1.13) | 0.01 | - | - | - | - | - |
| FiO2 at 60 min (%) | 1.4 | 1.15 (1.00–1.31) | 0.05 | 1.09 (1.01–1.17) | 0.02 | - | - | - | - | - |
| Hosmer–Lemeshow p-value = 0.91 | -2LL = 90 | Hosmer–Lemeshow p-value = 0.33 | -2LL: 129 | |||||||
2LL: − 2 log-likelihood statistic, BROSJOD score, bronchiolitis score of Sant Joan de Déu, CI confidence interval, HR heart rate, OR odds ratio, RR respiratory rate, VIF variance inflation factor
*Forward selection of variables; **Enter method of variables