Table 2.

Characteristics of the studies included in the metanalysis

Study	Population and treatment	Follow-up (months)	ABG closure	p value
Angeli (2006)	27 pts received 0.2 ml of HA before fenestration and subsequently adipose tissue grafts around the piston 32 patients received only adipose tissue grafts around the piston	15.5–13.7	6.6 ± 5.2 dB for the HA 7.6 ± 5.3 for the no HA group (p = 0.4)	0.4
Faramarzi (2019)	86 patients received an adipose graft 90 patients received a gelfoam graft	6	10.2 ± 6.7 for the adipose group 11.3 ± 8.6 for the gelfoam group	0.532
Bawazeer (2020)	215 patients received the gelfoam to seal the oval window after fenestration 203 control patients (without sealing)	12	4.6 ± 5.7 in the gelfoam group 5.3 ± 6.9 in the control group	0.634
Faramarzi (2021)	73 patients received 0.5 ml HA around the piston and in the middle ear cavity, 73 patients received lobule fat graft around the piston	6	14.6 ± 7.2 dB for the HA 16.3 ± 6.7 dB for the fat	0.337
Pradhan (2020)	26 patients received adipose tissue in sealing the oval window after insertion of the piston, 25 patients received gelfoam in sealing the oval window after insertion of the piston	3	13.92 ± 6.8 dB in the adipose group 15.42 ± 7.5 dB in the gelfoam group	0.56
Schmerber (2004)	314 subjects received vein graft interposition 128 subjects received tragal perichondrium	4	4.88 ± 5.77 dB in the adipose group 6.23 ± 6.10 dB in the gelfoam group	0.614