FIGURE 7.

The absence of FXR blocked the effect of Rc on suppressing inflammation in DSS-induced FXR^−/− mice. Serum levels of IL-1β, IL-6, and TNF-α (A–C); the colons were collected for qPCR analysis, and the relative mRNA levels of ICAM (D), COX-2 (E), and IL-6 (F) were measured; representative images of immunofluorescence of F4/80 (G) and cd11b (H) in mouse colon sections (magnification: 200 ×). Data are shown as the mean ± SEM (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001 vs. the saline group.