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. 2022 Nov 10;13:6803. doi: 10.1038/s41467-022-34568-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The regulatory network of RBPs and transcripts. b The numbers of regulated transcripts for each RBP. c The numbers of transcripts regulated by different numbers of RBPs. d The bubble plot shows the enrichment of regulated transcripts in biological hallmarks across different RBPs. Bubbles with FDR values <0.05 are labeled with black borders. e Comparisons of enrichment among different categories of RBPs (n = 13 RBPs for “spliceosome” category, n = 28 for “splicing regulation” category, n = 15 “modification & processing” category, n = 15 for “stability & decay” category). Each box represents the IQR and median of enrichment scores for each category, whiskers indicate 1.5 times IQR. P, two-sided Wilcoxon’s rank-sum test p-value.