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. 2022 Nov 10;13:6807. doi: 10.1038/s41467-022-34403-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Waterfall plot of tumor regression by pathology (n = 33). b Representative radiological and pathological images (HE staining, ×40, ×200) from responsive (NP025) and nonresponsive (NP018) patients. HE staining was performed one time in 33 independent samples with similar results. c Representative pathological features (HE staining, ×200) after immunotherapy. HE staining was performed one time in 33 independent samples with similar results. CPS combined positive score, UTA unable to access, GEJ gastroesophageal junction, MPR major pathologic response, HE hematoxylin and eosin, TLS tertiary lymphoid structures, TILs tumor-infiltrating lymphocytes. Source data are provided as a Source Data file.