Table 4.
Adjusted Odds Ratios (OR)* and 95% Confidence Intervals (CI) for INH adherence <90% in the prior 3 months (n = 539 observations; n = 279 participants) – stratified by social desirability score at baseline.
| Low/moderate SDSx | High SDS x x | |||
|---|---|---|---|---|
| Adjusted OR (95% CI) | p-value | Adjusted OR (95% CI) | p-value | |
| Alcohol use**, prior 3 months | 0.03 | 0.04 | ||
| None | 1.00 | 1.00 | ||
| Moderate | 1.81 (0.81, 4.06) | 1.37 (0.65, 2.86) | ||
| Unhealthy | 3.03 (1.33, 6.94) | 2.60 (1.22, 5.54) | ||
| Age (per 1 year decrease) | 1.04 (1.00, 1.07) | 0.04 | 1.06 (1.01, 1.10) | 0.01 |
| Gender | 0.58 | 0.54 | ||
| Female | 1.00 | 1.00 | ||
| Male | 1.21 (0.62, 2.38) | 1.27 (0.59, 2.76) | ||
| Depression | 0.51 | 0.64 | ||
| No | 1.00 | 1.00 | ||
| Yes | 1.30 (0.59, 2.87) | 1.76 (0.16, 19.12) | ||
| Grade 2+ LEEs or symptomsα | 0.47 | 0.21 | ||
| No | 1.00 | 1.00 | ||
| Yes | 1.29 (0.64, 2.63) | 1.61 (0.77, 3.37) | ||
| Low social support | 0.75 | 0.60 | ||
| No | 1.00 | 1.00 | ||
| Yes | 0.90 (0.47, 1.73) | 0.81 (0.38, 1.76) | ||
| ART adherence, prior 30 days | 0.02 | 0.01 | ||
| Good/fair/poor/very poor | 2.41 (1.13, 5.15) | 2.47 (1.21, 5.05) | ||
| Excellent/very good | 1.00 | 1.00 | ||
| Study visit | <0.01 | <0.01 | ||
| 3 months | 1.00 | 1.00 | ||
| 6 months | 1.96 (1.27, 3.01) | 1.76 (1.17, 2.66) | ||
*
GEE logistic regression models, exchangeable working correlation with robust empirical std errors
x
n = 271 observations; n = 141 participants
x x
n = 268 observations; n = 138 participants
**
Alcohol use: None: no self-report, PEth < 8; Moderate: any self-report but AUDIT-C negative; 8 <= PEth < 50; Unhealthy: AUDIT-C positive or PEth >= 50
α
Grade 2 or higher symptoms or liver enzyme elevations (LEEs) ≥2x upper limit of normal, in the prior 3 months