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. 2022 Aug 30;28:100400. doi: 10.1016/j.pacs.2022.100400

Fig. 7.

Fig. 7

Safety of the US assisted shaking of intravesical instilled GNRs@Chit-Iso4. Hematoxylin/eosin staining of mice bladder seven days after intravesical administration of A) GNRs@Chit-Iso4 (30 nmol Au, equivalent to 27 mEU of LPS) or B) LPS (5 EU), followed by US-assisted shaking for 12 min and two intravesical washes. * ; inflammatory infiltrate in the lamina propria, * *; hyperplasia of the urothelium, arrowhead; apoptotic bodies. Low and high magnification are shown on the left and right panels, respectively. C) Bioluminescent imaging of mice at day 7 after intravesical instillation of MB49-Luc cells (left), and at day 7 after intravesical instillation of 3 nmol GNRs@Chit-Iso4 and US-assisted shaking.