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. 2022 Nov 8;23:1–15. doi: 10.1016/j.bioactmat.2022.10.004

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — In vitro cytotoxicity of 5-FU + DDP combination against MKN45-luc cells. (A) Cytotoxicity research of 5-FU, DDP, and combined 5-FU + DDP with different drug ratios as a function of the total drug concentration after incubation for 24 h. Data are presented as mean ± sd (n = 5). (B) The CI values of free 5-FU and DDP combination at different drug ratios after co-incubating for 24 h. (C) Cytotoxicity study of 5-FU, DDP, and combined 5-FU + DDP with different drug ratios as a function of the total drug concentration after incubation for 48 h. Data are presented as mean ± sd (n = 5). (D) The CI values of 5-FU and DDP combination at different drug ratios after incubation for 48 h.