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Overview of (pMETTL14+RS09)@cRGD-M in dual-targeted tumor therapy. (A) (pMETTL14+RS09)@cRGD-M nanovesicles had the ability of dual-targeting tumor and macrophages. (B) (pMETTL14+RS09)@cRGD-M nanovesicles could target to inhibit tumor and induce M1 polarization of macrophages, thereby achieving the dual purposes of tumor inhibition and macrophage polarization.
