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. 2022 Oct 20;25(11):105417. doi: 10.1016/j.isci.2022.105417

Figure 5.

Figure 5

Enzymatic activity and PDI localization along the processing pathway

(A) Normalized enzymatic activities in the Golgi. The values of enzymatic activity toward PDI obtained by the model were normalized to 1 arbitrary unit and plotted in function of the total Golgi length set to 1.

(B) Normalized enzymatic activities in the endosomes. The values of enzymatic activity toward PDI obtained by the modeled were normalized to 1 arbitrary unit and plotted in function of the total endosomes’ length set to 1.

(C) Intracellular localization of PDI. The pie chart presents the relative amount in % of PDI calculated to be localized in the ER, Golgi, endosomes, and lysosomes by the model.