Table 4.

Univariable analysis for overall survival.

Variable	HR (95%CI)	P
Gender (Female)	1.474 (0.852, 2.550)	0.165
Age (≥65yr)	1.402 (0.816, 2.406)	0.221
Tumor location		0.008
UGEJ	1
Middle third	2.227 (0.936, 5.301)	0.070
Lower third	1.405 (0.619, 3.189)	0.417
Diffuse	4.539 (1.637, 12.581)	0.004
Tumor size (≥5cm)	3.092 (1.684, 5.680)	< 0.001
ypT		0.001
0	1
1-2	0.810 (0.084, 7.791)	0.885
3-4	6.235 (0.864, 45.012)	0.070
ypN		< 0.001
0	1
1	3.280 (1.456, 7.390)	0.004
2	2.928 (1.264, 6.783)	0.012
3	8.676 (4.192, 17.956)	< 0.001
ypTNM (III)	4.442 (2.456, 8.036)	< 0.001
Histological type	1.167 (0.716, 1.904)	0.535
Lauren classification	1.925 (1.178, 3.144)	0.009
Grade of differentiation	2.733 (1.303, 5.731)	0.008
Vascular or lymphatic invasion	1.901 (1.126, 3.210)	0.016
Nervous invasion	1.256 (0.716, 2.206)	0.427
Mandard TRG (3–5)	2.861 (1.557, 5.260)	0.001
Post-treatment
CD10 (+)	1.832 (1.053, 3.189)	0.032
FAP (+)	1.843 (1.139, 2.983)	0.013
GPR77 (+)	1.329 (0.657, 2.690)	0.429
Pre-treatment
CD10 (+)	1.293 (0.676, 2.475)	0.437
FAP (+)	0.698 (0.373, 1.305)	0.260
GPR77 (+)	0.977 (0.422, 2.265)	0.957

UGEJ, upper third and gastroesophageal junction; TRG, tumor regression grade. Bold values means significant.