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. 2022 Oct 28;13:999811. doi: 10.3389/fphys.2022.999811

TABLE 2.

Oxidation stress response with placebo (PLA), low-dosage caffeinated energy drink (Low ED) group and high-dosage caffeinated energy drink (High ED) group before and after participation in a sprint triathlon. *Significant difference at p < 0.05.

PLA Low ED High ED Main effect p vs. L p vs. H L vs. H
Mean ± SE F p p-value (Cohen’s d)
SOD (U/ml)
Pre 2.1 ± 0.3 2.1 ± 0.3 2.1 ± 0.3 0.0 0.96
Post 1.8 ± 0.2 1.7 ± 0.3 1.6 ± 0.3 4.1 0.03* p = 0.12 p = 0.02*(0.2) p = 0.02*(0.2)
p-value p = 0.01* p = 0.01* p = 0.00*
Catalase (nmol/min/ml)
Pre 46.8 ± 3.8 44.8 ± 1.8 49.0 ± 7.3 0.19 0.83
Post 68.6 ± 4.2 63.5 ± 3.9 63.7 ± 2.7 1.7 0.20
p-value p = 0.00* p = 0.00* p = 0.03*
TBARS (μM)
Pre 7.2 ± 1.6 10.2 ± 1.6 13.0 ± 3.8 1.5 0.25
Post 13.2 ± 4 5.9 ± 0.6 6.0 ± 0.8 3.8 0.04* p = 0.04*(0.8) p = 0.03*(0.7) p = 0.46
p-value p = 0.07 p = 0.02* p = 0.03*
GSH (μg/ml)
Pre 11.8 ± 1.4 12.1 ± 1.1 13.2 ± 1.7 0.44 0.65
Post 13.4 ± 1.6 13.8 ± 1.9 13.0 ± 2.3 0.14 0.87
p-value p = 0.19 p = 0.13 p = 0.45
GSSG (μg/ml)
Pre 181.3 ± 20.3 194.3 ± 13.4 184.1 ± 10.5 0.3 0.76
Post 184.5 ± 18.7 183.1 ± 12.2 186.5 ± 13.1 0.0 0.98
p-value p = 0.43 p = 0.20 p = 0.44
GSH/GSSG(μg/ml)
Pre 0.08 ± 0.02 0.06 ± 0.01 0.07 ± 0.01 0.7 0.50
Post 0.08 ± 0.01 0.08 ± 0.01 0.07 ± 0.01 0.3 0.76
p-value p = 0.45 p = 0.10 p = 0.48