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. 2022 Oct 27;10(4):244–254. doi: 10.14791/btrt.2022.0030

Table 2. Progression-free survival rates in intracranial anaplastic meningioma.

Variables No. of progression/no. of patients (%) Univariate analysis Multivariate analysis
Survival (month, mean±SE) p value (log-rank) HR 95% CI p value
Overall 34/48 (70.8) 13.9±2.6 -
Age (years) 0.552
<57 16/20 (80.0) 9.6±10.4
≥57 18/28 (64.3) 13.9±1.7
Sex 0.016 1.387 0.673–2.859 0.375
Male 18/30 (60.0) 28.4±8.7
Female 16/18 (89.9) 8.8±1.9
Diagnosis type <0.001 1.569 0.614–4.006 0.346
Primary 16/28 (57.1) 29.7±10.9
Secondary 18/20 (90.0) 5.7±0.8
Location 0.080 1.987 0.923–4.278 0.079
Superficial 22/35 (62.9) 17.9±8.1
Deep or skull base 12/13 (92.3) 6.2±3.9
Tumor size 0.083
<4.5 cm 17/19 (89.5) 12.5±3.7
≥4.5 cm 17/29 (58.6) 26.7±13.4
Peritumoral edema 0.668
Mild 12/18 (66.7) 14.7±6.3
Moderate to severe 22/30 (73.3) 13.9±4.7
Tumor shape 0.470
Round 13/17 (76.5) 13.9±2.2
Mushroome 21/31 (67.7) 15.4±5.9
Preoperative ECOG 0.278
0 or 1 15/24 (62.5) 17.3±10.3
≥2 19/24 (79.2) 13.0±3.3
Extent of resection <0.001 1.896 0.858–4.191 0.114
GTR 22/36 (61.1) 26.7±9.6
STR 12/12 (100) 5.7±0.6
Simpson grade 0.125
1 or 2 20/31 (64.5) 17.9±9.6
3 or 4 or 5 14/17 (82.4) 8.8±3.5
Adjuvant radiation <0.001 0.113 0.034–0.374 <0.001
No 15/16 (93.7) 4.4±0.7
Yes 19/32 (59.4) 29.7±4.2

SE, standard error; HR, hazard ratio; 95% CI, 95% confidence interval; ECOG, Eastern Cooperative Oncology Group; GTR, gross total resection; STR, subtotal resection