FIG. 4.
Effect of depletion of nylon wool-adherent cells from
spleens of L3-infected mice on mitogen-driven responses. Mice were
injected as described in the legend to Fig. 1. Spleen cells from five
mice in each group were pooled. Splenic T cells from L3-infected mice,
purified by passing the pooled spleen cell suspension over nylon wool
columns, were incubated with irradiated syngeneic spleen cells from
uninfected mice
(▨) or with
irradiated spleen cells from L3-infected mice
(▩).
ConA-stimulated proliferation (A) and cytokine production (B to F) were
measured in these cultures and in cultures of unseparated spleen cells
from L3-infected
(
) and
uninfected (
)
mice.