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. 2022 Nov 11;4(Suppl 2):ii53–ii60. doi: 10.1093/noajnl/vdac035

Table 1.

 Analysis of Intact Extracellular Vesicles (EVs) From Plasma of Patients With Glioma

Biomarker Method Study
EV count, Annexin V Cryo-electron microscopy (CM)
Flow cytometry (FCM)
Evans et al13
EV count, Annexin V FCM
Electron microscopy (EM)
Koch et al14
EV count and characterization Nanoparticle tracking analysis (NTA) Cumba Garcia et al15
EV count and characterization NTA
Confocal laser scanning microscopy (CLSM)
Osti et al16
EV count and size NTA
Transmission electron microscopy (TEM)
Akers et al17
EV size and count, CD63, CD81, CD9 NTA
TEM
Imaging flow cytometry (IFCM)
Correlative light electron microscopy (CLEM)
Ricklefs et al18
EGFR, EGFRvIII, PDGFR, PDPN, EphA2 and IDH1, R132H Size and immunoaffinity
Microfluidic nuclear magnetic resonance (µNMR) assay
Shao et al19
Total protein quantification FCM
TEM
Muller et al20