Table 2.
Rate of prenatal cannabis use per 100 pregnancies before and during the COVID-19 pandemic by pre-conception depression and anxiety status.
| Multiplicative modela | Additive modela | |||||
|---|---|---|---|---|---|---|
| Pre-conception depression and anxiety status | Standardized rate before COVID-19 | Standardized rate during COVID-19 | During COVID-19 vs. before COVID-19, rate ratio (95% CI) | p-value relative to neither depression nor anxiety | During COVID-19 vs. before COVID-19, rate difference (95% CI) | p-value relative to neither depression nor anxiety |
| Neither depression nor anxiety | 6.3 | 7.5 | 1.20 (1.14,1.27)* | ref | 0.58 (0.35,0.81)* | ref |
| Depression only | 13.9 | 14.7 | 1.06 (0.84,1.33) | 0.29 | 1.21 (-1.75,4.17) | 0.68 |
| Anxiety only | 10.2 | 11.1 | 1.07 (0.88,1.30) | 0.25 | 0.44 (-1.43,2.31) | 0.88 |
| Comorbid depression and anxiety | 14.6 | 20.6 | 1.40 (1.14,1.72)* | 0.16 | 5.89 (2.40,9.38)* | <0.01 |
* Significant at p<=0.05
a
Poisson models included adjustment for age and race.