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. 2022 Oct 25;10:975786. doi: 10.3389/fbioe.2022.975786

TABLE 1.

OX5034 Aedes aegypti homozygote, hemizygote and WT penetrance on and off doxycycline. Percentages are means of L1 individuals reaching the specified stage based on initial counts of 200 L1 larvae per repeat (5 repeats) and assuming a 1:1 sex ratio. 95% confidence intervals are displayed in parentheses. Note that in the case of female OX5034 progeny, zero female adults (functional or otherwise) were identified in any of the crosses without doxycycline.

Cross Doxycycline concentration (µg/ml) Male progeny Female progeny
% Total Eclosion % Functional Adults % Total Eclosion % Functional Adults
OX5034 ♂ x OX5034 ♀ 0 69.8 (±8.8) 63.6 (±8.1) (±0.0) (±0.0)
4 63.2 (±8.0) 58.8 (±9.1) 47.5 (±6.0) 43.0 (±6.8)
OX5034 ♂ x WT ♀ 0 87.2 (±5.5) 61.4 (±5.5) (±0.0) (±0.0)
4 87.7 (±5.5) 69.0 (±7.3) 75.3 (±5.9) 65.4 (±9.1)
OX5034 ♀ x WT ♂ 0 70.6 (±11.2) 68.4 (±10.5) (±0.0) (±0.0)
4 70.8 (±5.1) 68.0 (±5.9) 59.0 (±3.3) 57.8 (±3.6)
WT ♂ x WT ♀ 0 65.0 (±3.9) 62.6 (±4.2) 60.3 (±5.4) 57.2 (±5.3)
4 69.2 (±3.2) 67.6 (±3.3) 80.5 (±7.0) 76.8 (±7.1)