Table 1. Psychological vs. somatic effects*.

*[10]

The author has uploaded the figure on the internet for free use

Psychological effects in animals and humans [in medium dose (12–20 mg p.o.)]

Somatic adverse effects in humans (barely noticeable/secondary pharmacological effects)

Affective activation, hypnagogia, dreams, introspection, mystical-type experience, which predicts the success of the therapy and likelihood of benefits, hallucination, synaesthesia, alterations of time sense

At 8–12 mg p.o., i.m.; mydriasis, increased heartbeat frequency, decreased heartbeat frequency, hypotension, hypertension, nausea, increased reflex tendineae, decreased reflex tendineae, dysmetria, tremors. Similar results were noted in another trial at 0.11 mg/kg p.o. Other studies found no significant aberrations in the above-mentioned effects at 1.5 mg raised to 25 mg p.o. in three doses each day for 21 consecutive days