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. Author manuscript; available in PMC: 2022 Nov 14.
Published in final edited form as: Immunohorizons. 2022 Jul 25;6(7):528–542. doi: 10.4049/immunohorizons.2200050

FIGURE 7. Heightened inflammation in SPexp mice contributes to increased mortality to CLP.

FIGURE 7.

(A) Experimental design. CLP was induced 5 or 90 d after last infection in SPexp B6 mice or in age-matched SPfree B6 mice. Body weight and mortality were monitored over time. Serum was collected before surgery. (B) Summary data of analyte concentrations (pg/ml) before CLP. (C–E) Weight loss (C), clinical score (D), and mortality (E) after CLP. Data are representative of at least two independent experiments with nine mice per group. Error bars represent SEM. *p < 0.05, **p < 0.01, ***p < 0.001.