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Differences in serum levels of periostin based on disease type and duration. Scatterplot showing distribution of serum periostin levels in controls (HC), dcSSc and lcSSc patients in A and in early (under 3 years) or late (over 3 years) SSc. Bars represent mean and standard deviation, analyzed by Kruskal-Wallis test with Dunn’s multiple comparisons test in A and unpaired Mann-Whitney test in B (GraphPad Prism 9); p < 0.05 *, p < 0.01**, p < 0.001***, p < 0.0001****
