Table 3.
Comparison of serum periostin levels according to categorical clinical variables in SSc patients
| Variable | N | periostin (ng/ml)) | p value |
|---|---|---|---|
| Sex | |||
| F | 88 | 133.0 ± 128.0 | 0.005 |
| M | 18 | 251.5 ± 201.6 | |
| Disease subtype | |||
| lcSSc | 77 | 130.9 ± 133.7 | 0.001 |
| dcSSc | 29 | 211.9 ± 172.3 | |
| ILD | |||
| Y | 58 | 153.1 ± 144.1 | 0.40 |
| N | 48 | 153.1± 156.0 | |
| PAH | |||
| Y | 33 | 145.4 ± 162.3 | 0.47 |
| N | 73 | 156.6 ± 143.4 | |
| Digital ulcers, past or current | |||
| Y | 14 | 230.5 ± 175.9 | 0.22 |
| N | 45 | 154.0 ± 149.8 | |
| Pitting scars, past or current | |||
| Y | 25 | 174.6 ± 167.1 | 0.75 |
| N | 38 | 154.7 ± 145.1 | |
| Teleangiectasias | |||
| Y | 27 | 161.1 ± 171.1 | 0.35 |
| N | 26 | 190.9 ± 154.3 | |
| Current/former smoker | |||
| Y | 41 | 160.2 ± 162.2 | 0.96 |
| N | 51 | 142.4 ± 137.4 | |
| Joint contractures | |||
| Y | 14 | 220.7 ± 165.7 | 0.06 |
| N | 43 | 140.8 ± 125.2 | |
F Female, M Male, N Number of patients with available information, lcSSc Limited scleroderma, dcSSc Diffuse scleroderma, ILD Interstitial lung disease, PAH Pulmonary arterial hypertension, Y Yes, N No. Data are presented as mean ± standard deviation. Mann-Whitney test was used for analyses