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. 2022 Oct 11;14(10):e30206. doi: 10.7759/cureus.30206

Table 4. Reported cases of renal-associated AAV induced by COVID-19 vaccination.

ANCA: antineutrophil cytoplasmic antibody; AAV: ANCA-associated vasculitis; MPO: myeloperoxidase; PR3: proteinase 3.

Authors Age/sex COVID-19 vaccine type Onset of symptoms Clinical presentation ANCA positivity Management
Shakoor et al. [4] 79/F Pfizer-BioNTech (second dose) 2 weeks Weakness, upper thigh pain, acute kidney injury MPO-ANCA Steroids, cyclophosphamide
Dube et al. [6] 29/F Pfizer-BioNTech (second dose) 16 days Acute kidney injury MPO-ANCA Steroids, rituximab, cyclophosphamide
Takenaka et al. [7] 75/F Pfizer-BioNTech (first dose) 4 days Blurred vision MPO-ANCA Steroids
Sekar et al. [8] 52/M Moderna (second dose) 2 weeks Headache, weakness, acute kidney injury PR3-ANCA Steroids, cyclophosphamide
Anderegg et al. [9] 81/M Moderna (second dose) Not reported Flu-like symptoms, acute kidney injury PR3-ANCA Steroids, cyclophosphamide, plasma exchange therapy
Al-Yafeai et al. [10] 62/F Pfizer-BioNTech (first dose) 4 weeks Weakness, hematemesis, arthralgia, acute kidney injury PR3-ANCA Steroids, cyclophosphamide, plasma exchange therapy