Table 2.
Incidence of any and all psychological morbidities among adults with and without CP or SB with one-year clean enrollment period.
| †No Outcome at Baseline | ||
|---|---|---|
| Case/Denominator | Control/Denominator | |
| Any Psychological Morbidity | 4205/10848 (38.8%)* | 395275/1635348 (24.2%) |
| Insomnia | 1402/14655 (9.6%)* | 105331/1884216 (5.6%) |
| Adjustment disorders | 767/14891 (5.2%)* | 63017/1905421 (3.3%) |
| Anxiety disorders | 2568/13560 (18.9%)* | 204060/1819089 (11.2%) |
| PTSD | 163/15193 (1.1%)* | 8416/1931162 (0.4%) |
| Delirium/Dementia/Amnestic/Other Cognitive Disorder | 990/14826 (6.7%)* | 41606/1916260 (2.2%) |
| Dementias | 351/15150 (2.3%)* | 19773/1929124 (1.0%) |
| Impulse control disorders NEC | 79/15236 (0.5%) | 1592/1934754 (0.1%) |
| Mood disorders | 2524/12898 (19.6%)* | 179935/1794787 (10.0%) |
| Personality disorders | 157/15229 (1.0%)* | 4790/1933048 (0.2%) |
| Alcohol-related disorders | 341/15112 (2.3%)* | 33777/1921455 (1.8%) |
| Substance-related disorders | 731/15043 (4.9%)* | 51119/1923254 (2.7%) |
| Central Pain | 1996/14391 (13.9%)* | 115911/1898453 (6.1%) |
*
P<.01 and standard mean difference (SMD) ≥0.2
†
Denominators for both cases and controls reflect a one-year clean period during their enrollment for the specific condition. For instance, among cases (CP/SB), there exist 14,655 patients whose first year of enrollment had no evidence of insomnia; therefore, inferred incident insomnia could be estimated for this subset of the full CP/SB cohort. As a result, all patient cohorts’ denominators dynamically change conditional on the incident outcome being measured to ensure a clean period in the first year of enrollment