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. 2022 Nov 10;11(11):e34075. doi: 10.2196/34075

Table 1.

Sample size required to detect certain antibody conversion rates with 95% CIs at different follow-up periods.

Individuals included and antibody conversion rate 4 weeks between follow-up 8 weeks between follow-up 12 weeks between follow-up
Secondary staff, approximate n=10,620

Antibody conversion, % (95% CI) 0.4 (0.2-0.6) 0.8 (0.5-1.1) 1.2 (0.9-1.5)

Converting, n (95% CI) 42 (21-64) 85 (53-117) 127 (96-159)
Secondary students, approximate n=20,400

Antibody conversion, % (95% CI) 0.4 (0.3-0.5) 0.8 (0.6-1.0) 1.2 (1.0-1.4)

Converting, n (95% CI) 82 (41-122) 163 (102-224) 245 (184-306)
Primary staff, approximate n=1440

Antibody conversion, % (95% CI) 0.4 (0.0-0.9) 0.8 (0.1-1.5) 1.2 (0.3-2.1)

Converting, n (95% CI) 6 (3-9) 12 (7-16) 17 (13-22)
Primary students, approximate n=8460

Antibody conversion, % (95% CI) 0.4 (0.2-0.6) 0.8 (0.5-1.1) 1.2 (0.8-1.6)

Converting, n (95% CI) 34 (17-51) 68 (42-93) 102 (76-127)