Table 3. Mean values for effects of the drugs on behavioral seizure parameters.
Groups | Behavioral seizure parameters | |||
---|---|---|---|---|
Onset time of first myoclonic jerk | onset time of generalized tonic-clonic seizure | duration of generalized tonic-clonic seizure | average seizure score | |
NS+PTZ | 63.3±3.8 | 81.2±4.4 | 41.4±3.2 | 5±0.0 |
5-HT+PTZ | 117.1±8.2 | 146.1±9.8 | 36.6±4.5 | 4.7±0.1 |
Fluoxt+PTZ | 145.5±16.1 | 199.0±14 | 39.6±3.4 | 4.7±0.1 |
Sumt+PTZ | 65.1±3.3 | 91.5±5.2 | 50.7±3.9 | 5±0.0 |
Values are presented as mean ± SEM. SEM: standard error of the mean; NS: normal saline; 5-HT: serotonin; fluoxt: fluoxetine; sumt: sumatriptan; PTZ: pentylenetetrazole; GTCS: generalized tonic-clonic seizures.