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. 2021 Nov 30;80(1):23–29. doi: 10.1590/0004-282X-ANP-2021-0012

Table 2. Data from ROC curves for comparisons between clinical groups (AD and non-AD) and controls, and between AD and non-AD patients.

Variable Naming Inc Mem Im Mem Learning DR Recognition VF CDT BCSB total
Clinical groups vs. Controls AUC 0.53 0.68 0.79 0.78 0.87 0.69 0.78 0.69 0.89
95% CI 0.43 to 0.62 0.58 to 0.76 0.71 to 0.86 0.69 to 0.851 0.79 to 0.92 0.59 to 0.77 0.69 to 0.85 0.59 to 0.78 0.83 to 0.95
Sensitivity 5.56 65.28 51.39 76.39 80.56 48.61 68.18 63.33 88.89
Specificity 100 64.44 93.33 71.11 77.78 86.67 80.00 75.56 81.94
Cutoff ≤ 8 ≤ 5 ≤ 6 < 8 < 7 ≤ 9 ≤ 13 ≤ 8 ≤ 68
AD vs. Controls AUC 0.53 0.71 0.82 0.82 0.91 0.70 0.75 0.67 0.89
95% CI 0.43 to 0.62 0.60 to 0.81 0.73 to 0.89 0.72 to 0.89 0.84 to 0.96 0.60 to 0.80 0.64 to 0.83 0.56 to 0.77 0.81 to 0.94
Sensitivity 5.57 71.11 57.78 82.22 68.89 51.11 67.44 62.16 80
Specificity 100.00 64.44 93.33 71.11 100 86.67 73.33 75.56 91.11
Cutoff ≤ 8 ≤ 5 ≤ 6 ≤ 8 ≤ 5 ≤ 9 ≤ 14 ≤ 8 ≤ 67
AD vs. non-AD AUC 0.51 0.58 0.58 0.60 0.69 0.55 0.63 0.54 0.50
95% CI 0.39 to 0.63 0.46 to 0.70 0.46 to 0.70 0.48 to 0.71 0.57 to 0.79 0.43 to 0.67 0.50 to 0.75 0.41 to 0.67 0.38 to 0.62
Sensitivity 100 71.11 57.78 53.33 53.33 26.67 72.09 64.86 80.00
Specificity 3.7 44.44 59.26 62.96 81.48 85.19 52.17 43.48 7.41
Cutoff > 5 ≤ 5 ≤ 6 ≤ 7 ≤ 4 ≤ 8 > 10 > 5 > 48

AUC: area under the curve; 95% CI: Confidence interval; Criterion: cutoff point; Inc. Mem.: incidental memory; Im. Mem.: immediate memory; DR: delayed recall; VF: verbal fluency; CDT: clock drawing test; BCSB: Brief Cognitive Screening Battery.