Table 2. Data from ROC curves for comparisons between clinical groups (AD and non-AD) and controls, and between AD and non-AD patients.
Variable | Naming | Inc Mem | Im Mem | Learning | DR | Recognition | VF | CDT | BCSB total | |
---|---|---|---|---|---|---|---|---|---|---|
Clinical groups vs. Controls | AUC | 0.53 | 0.68 | 0.79 | 0.78 | 0.87 | 0.69 | 0.78 | 0.69 | 0.89 |
95% CI | 0.43 to 0.62 | 0.58 to 0.76 | 0.71 to 0.86 | 0.69 to 0.851 | 0.79 to 0.92 | 0.59 to 0.77 | 0.69 to 0.85 | 0.59 to 0.78 | 0.83 to 0.95 | |
Sensitivity | 5.56 | 65.28 | 51.39 | 76.39 | 80.56 | 48.61 | 68.18 | 63.33 | 88.89 | |
Specificity | 100 | 64.44 | 93.33 | 71.11 | 77.78 | 86.67 | 80.00 | 75.56 | 81.94 | |
Cutoff | ≤ 8 | ≤ 5 | ≤ 6 | < 8 | < 7 | ≤ 9 | ≤ 13 | ≤ 8 | ≤ 68 | |
AD vs. Controls | AUC | 0.53 | 0.71 | 0.82 | 0.82 | 0.91 | 0.70 | 0.75 | 0.67 | 0.89 |
95% CI | 0.43 to 0.62 | 0.60 to 0.81 | 0.73 to 0.89 | 0.72 to 0.89 | 0.84 to 0.96 | 0.60 to 0.80 | 0.64 to 0.83 | 0.56 to 0.77 | 0.81 to 0.94 | |
Sensitivity | 5.57 | 71.11 | 57.78 | 82.22 | 68.89 | 51.11 | 67.44 | 62.16 | 80 | |
Specificity | 100.00 | 64.44 | 93.33 | 71.11 | 100 | 86.67 | 73.33 | 75.56 | 91.11 | |
Cutoff | ≤ 8 | ≤ 5 | ≤ 6 | ≤ 8 | ≤ 5 | ≤ 9 | ≤ 14 | ≤ 8 | ≤ 67 | |
AD vs. non-AD | AUC | 0.51 | 0.58 | 0.58 | 0.60 | 0.69 | 0.55 | 0.63 | 0.54 | 0.50 |
95% CI | 0.39 to 0.63 | 0.46 to 0.70 | 0.46 to 0.70 | 0.48 to 0.71 | 0.57 to 0.79 | 0.43 to 0.67 | 0.50 to 0.75 | 0.41 to 0.67 | 0.38 to 0.62 | |
Sensitivity | 100 | 71.11 | 57.78 | 53.33 | 53.33 | 26.67 | 72.09 | 64.86 | 80.00 | |
Specificity | 3.7 | 44.44 | 59.26 | 62.96 | 81.48 | 85.19 | 52.17 | 43.48 | 7.41 | |
Cutoff | > 5 | ≤ 5 | ≤ 6 | ≤ 7 | ≤ 4 | ≤ 8 | > 10 | > 5 | > 48 |
AUC: area under the curve; 95% CI: Confidence interval; Criterion: cutoff point; Inc. Mem.: incidental memory; Im. Mem.: immediate memory; DR: delayed recall; VF: verbal fluency; CDT: clock drawing test; BCSB: Brief Cognitive Screening Battery.