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. 2022 Nov 11;17(11):e0277511. doi: 10.1371/journal.pone.0277511

Table 3. Age-adjusted analyses of differences in late midlife (follow-up) among six adult-life trajectories of alcohol consumption.

Full sample n = 2510 men Abstaining n = 76 Moderate n = 1635 High-risk n = 119 Increasing n = 274 Decreasing n = 320 Fluctuating n = 86 P-valuea
Late Midlife Follow-up Data
Sociodemographic factors
Age at follow-up (continuous) 61.62 (3.27) 61.60 61.63 62.37* 62.03 61.13* 61.11 0.001
Years of Education (continuous) 13.58 (2.52) 13.03* 13.79 13.36 13.61 12.73*** 13.31 <0.001
Job (binary) 65.30% 0.59 0.69 0.49*** 0.62* 0.55*** 0.63 <0.001
Partner (binary) 81.79% 0.76 0.85 0.68*** 0.83 0.71*** 0.73* <0.001
Children (binary) 82.11% 0.76 0.86 0.75** 0.77** 0.74*** 0.77 <0.001
Intelligence (continuous)
Intelligence (IQ) 94.91 (14.64) 91.50* 96.06 93.43 93.75* 91.69*** 93.73 <0.001
IQ change -5.09 (9.33) -4.33 -4.93 -6.75 -5.69 -4.94 -5.29 0.490
Personality (continuous)
Neuroticism z-score 0.08 -0.04 -0.01 0.07 0.10* 0.05 0.222
Extraversion z-score -0.23* 0.03 0.12 0.02 -0.14*** -0.12 0.017
Openness z-score -0.01 -0.00 0.13 -0.07 0.05 -0.08 0.551
Agreeableness z-score -0.10 0.04 -0.03 0.05 -0.16** -0.16 0.026
Conscientiousness z-score -0.07 0.05 -0.04 -0.01 -0.19*** -0.17* 0.006
Lifestyle
Smoking: Pack Years (count) 19.51 (26.90) 15.42 15.67 34.64*** 21.89** 29.58*** 30.54*** <0.001
Years with weekly Extreme Binge Drinking (count) 3.93 (9.49) 0.06*** 1.78 17.51*** 5.79*** 8.46*** 6.51*** <0.001
Physical activity (continuous) z-score -0.30** 0.08 -0.16* -0.10** -0.15*** -0.19* <0.001
BMI (continuous) 26.59 (4.05) 27.69** 26.28 28.10*** 26.83* 27.19*** 26.56 <0.001
BMI change (continuous) 5.17 (3.67) 6.27** 4.91 6.35*** 5.34 5.64** 5.29 <0.001
Self-reported Health (binary)
Good Physical health 85.98% 0.82 0.90 0.76** 0.83** 0.76*** 0.79* <0.001
Good Mental health 91.21% 0.87 0.93 0.84** 0.88** 0.87** 0.89 <0.001
Major Depression Inventory (continuous) 5.47 (6.34) 6.99 4.73 7.91*** 6.37*** 6.93*** 6.75** <0.001
High Blood Pressure 37.22% 0.30 0.36 0.46* 0.38 0.41 0.44 0.088
High Cholesterol 32.19% 0.26 0.30 0.39 0.36 0.35 0.37 0.083
Diabetes 8.79% 0.12 0.07 0.18** 0.08 0.13** 0.17* <0.001
Heart attack 5.67% 0.12 0.05 0.04 0.05 0.09* 0.06 0.108
Stroke 4.35% 0.09 0.03 0.07 0.06 0.08** 0.07 0.001
Concussion 35.84% 0.30 0.34 0.45* 0.32 0.45** 0.37 0.002
Treatment for alcohol problems 10.32% No data 0.04 0.35*** 0.10** 0.32*** 0.23*** <0.001

a P-value for overall test of differences among the six trajectories

* P < 0.05

** P < 0.01

*** P < 0.001