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. 2022 Nov 11;17(11):e0277511. doi: 10.1371/journal.pone.0277511

Table 4. Birthdate-adjusted analyses of differences in comorbidity index and prevalence of hospital admission diagnoses (registry data) among six adult-life trajectories of alcohol consumption.

Full sample n = 2510 men Abstaining n = 76 Moderate n = 1635 High-risk n = 119 Increasing n = 274 Decreasing n = 320 Fluctuating n = 86 P-valuea
Registry Data (binary)
Charlson Comorbidity Index (count) 0.87 (1.62) 1.07 0.73 1.58** 0.83 1.23*** 1.33** <0.001
Alcohol-related disorders 8.17% 0.03 0.04 0.26*** 0.07* 0.25*** 0.15** <0.001
Substance abuse 2.11% 0.05 0.01 0.03 0.02 0.07*** 0.02 <0.001
Psychotic disorders 4.70% 0.10* 0.03 0.03 0.06 0.08** 0.10* 0.001
Mood disorders 10.04% 0.15 0.08 0.17* 0.09 0.15** 0.12 0.003
Neurosis/Anxiety disorders 6.45% 0.16** 0.05 0.09 0.08 0.09** 0.11 0.002
Adjustment disorders 12.43% 0.24** 0.10 0.17* 0.11 0.17** 0.22* <0.001
Personality disorders 8.76% 0.20** 0.06 0.14* 0.10* 0.17*** 0.11 <0.001

a P-value for overall test of differences among the six trajectories

* P < 0.05

** P < 0.01

*** P < 0.001