TABLE 2.
Survival of S. pyogenes in human blood
| Strain | Relevant pheno-type | CFU/mla after time (h)
|
MF (3 h)b | |||
|---|---|---|---|---|---|---|
| 0 | 1.5 | 3 | 4.5 | |||
| AP1 (wild type) | M+ H+ | 380 | 7.6 × 103 | 8.9 × 104 | ndc | 234 ± 68 |
| MC25 | M− H+ | 340 | 2.1 × 103 | 2.2 × 104 | nd | 64 ± 17 |
| BM27.6 | M+ H− | 220 | 2.0 × 103 | 2.8 × 104 | nd | 127 ± 35 |
| BM22.1 | M− H− | 300 | 0 | 0 | 0 | 0 |
| BM22.1/pBH | M− H+ | 200 | 520 | 1.6 × 103 | 7.8 × 103 | 8 ± 2 |
a
The data represent the means of at least two independent bactericidal assays.
b
The increases in titers (multiplication factor [MF]) after 3 h of incubation in human blood are given as means ± standard deviations.
c
nd, not determined.