Table 3.
Community-onset and hospital-onset BSI pathogen comparison pre-pandemic and pandemic periods
| Pathogen | Pre-pandemic: July 2019-February 2020 (n = 1,789,449 admissions) |
Pandemic period March 2020-September 4, 2021 (n = 3,450,243 admissions) |
||
|---|---|---|---|---|
| Community-onset BSI rate/1000 Adm (n) | Hospital-onset BSI rate/1000 Adm (n) | Community-onset BSI rate/1000 Adm (n) | Hospital-onset BSI rate/1000 Adm (n) | |
| Gram-negative | ||||
| E coli | 3.78 (6764) | 0.23 410) | 3.77 (13,001) | 0.22 (766) |
| K pneumoniae | 0.93 (1,662) | 0.14 (250) | 1.00 (3456)a | 0.17 (597)b |
| P aeruginosa | 0.39 (697) | 0.08 (141) | 0.37 (1275) | 0.11 (384)b |
| P mirabilis | 0.35 (622) | 0.02 (39) | 0.38 (1,294) | 0.03 (89) |
| E cloacae | 0.18 (318) | 0.06 (102) | 0.18 (610) | 0.06 (207) |
| S marcescens | 0.12 (208) | 0.04 (64) | 0.14 (477)a | 0.06 (192)b |
| B fragilis | 0.10 (171) | 0.02 (35) | 0.10 (339) | 0.02 (65) |
| K oxytoca | 0.09 (153) | 0.02 (40) | 0.11 (384)a | 0.02 (65) |
| K (E) aerogenes | 0.07 (126) | 0.02 (41) | 0.07 (236) | 0.03 (88) |
| A baumannii spp | 0.05 (91) | 0.01 (22) | 0.04 (141) | 0.02 (56) |
| P stuartii | 0.02 (33) | < 0.01 (3) | 0.02 (86) | < 0.01 (14) |
| S maltophilia | 0.02 (36) | 0.01 (23) | 0.02 (62) | 0.01 (42) |
| M morganii | 0.04 (70) | 0.01 (10) | 0.06 (191)a | 0.01 (25) |
| C freundii | 0.03 (49) | < 0.01 (8) | 0.03 (103) | < 0.01 (16) |
| Gram-positive | ||||
| S aureus | 2.81 (5035) | 0.45 (812) | 3.05 (10,511)a | 0.58 (2,016)b |
| Enterococcus spp | 0.64 (1152) | 0.16 (283) | 0.74 (2559)a | 0.25 (874)b |
| S pneumoniae | 0.42 (751) | 0.01 (12) | 0.23 (807)a | 0.01 (39) |
| Grp B Strep | 0.42 (759) | 0.01 (26) | 0.45 (1543)a | 0.02 (59) |
| Grp A Strep | 0.25 (443) | 0.01 (12) | 0.19 (651) | < 0.01 (13) |
| Fungus/Yeast | ||||
| Non-C albicans | 0.11 (202) | 0.10 (181) | 0.10 (329) | 0.15 (533)b |
| C albicans | 0.07 (121) | 0.08 (147) | 0.05 (189) | 0.13 (446)b |
| Other—Candida | < 0.01 (2) | < 0.01 (6) | < 0.01 (2) | < 0.01 (6)b |
| Pathogen | Pre-pandemic: July 2019- February 2020 (n = 1,789,449 admissions) |
Pandemic period March 2020- September 4, 2021 (n = 3,450,243 admissions) |
||
|---|---|---|---|---|
| Community-onset BSI rate/1000 Adm (n) | Hospital-onset BSI rate/1000 Adm (n) | Community-onset BSI rate/1000 Adm (n) | Hospital-onset BSI rate/1000 Adm (n) | |
| Polymicrobial | 0.36 (648) | 0.06 (104) | 0.42 (1,458)a | 0.08 (272)b |
aP ≤ 0.0404 for community (CO) pandemic period vs. pre-pandemic period; bP ≤ 0.0093 for HO pandemic period vs pre-pandemic period