Figure 7. Effects of CEACAM1 neutralizing antibody on β-GPs-induced HO-1 mRNA expression in RT7 cells.

Cells were pre-incubated with the neutralizing antibody for CEACAM1 and mouse IgG as the negative control (each 10 μg/mL) for 1 hour, then exposed to C. albicans β-glucan-containing particles (CA β-GPs) (200 μg/mL) for 12 hours. HO-1 mRNA levels are shown as relative to that of β-actin. Values are shown as fold increase as compared to the control cells and presented as the mean ± SD of three independent experiments. #Significant decrease as compared with C. albicans β-GPs alone (Bonferroni/Dunn's multiple comparison test: p<0.05).